Treatment of Gonorrhea
Gonococci are resistant to the commonly
used antimicrobials like penicillins and tetracyclines, and they are
avoided as a first choice option. Single-dose of intramuscular
ceftriaxone or oral cefixime can cure most cases of uncomplicated
gonorrhea. Single-dose oral ciprofloxacin, or levofloxacin is highly
effective for gonococcal infections acquired in the United States.
Gonorrhea patients should also be routinely treated for co-existing Chlamydia trachomatis infections, with azithromycin single dose or doxycycline twice daily for 1 week.
Disseminated gonococcal infection
patients are treated with injectable formulations such as ceftriaxone,
cefotaxime, ciprofloxacin, or levofloxacin for 1-2 weeks. Other
complicated gonorrhea infections may be treated orally for 1-2 weeks.
All partners in the past 60 days should also be treated.
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